Publications

2017

53. Issaadi, H. M.; Hunyadi, A.; Németh, K., Capillary electrophoresis study on the base-catalyzed formation of bioactive oxidized metabolites of 20-hydroxyecdysone, J. Pharm. Biomed. Anal. 2017, 146, 188-194.

52. Kozma, E.; Estrada Girona, G.; Paci, G.; Lemke, E. A.; Kele, P., Bioorthogonal Double-Fluorogenic Siliconrhodamine Probes for Intracellular Superresolution Microscopy, Chem. Commun. 2017, 53, 6696-6699.

51. Demeter, O.; Kormos, A.; Koehler, C.; Mező, G.; Németh, K.; Kozma, E.; Takacs, L.; Lemke, E. A.; Kele, P., Bisazide Cyanine Dyes as Fluorogenic Probes for Bis-cyclooctynylated Peptide Tags and as Fluorogenic Crosslinkers of Cyclooctynylated Proteins, Bioconjugate Chem. 2017, 28(5), 1552-1559.

50. Kozma, E.; Demeter, O.; Kele, P., Bioorthogonal Fluorescent Labelling of Biopolymers via Inverse Electron Demand Diels-Alder Reactions, ChemBioChem 2017, 18, 486–501.

 

2016

49. Quast, R. B.; Ballion, B.; Stech, M.; Sonnabend, A.; Varga, B. R.; Wüstenhagen, D. A.; Kele, P.; Schiller, S. M.; Kubick S., Cell-free synthesis of functional human epidermal growth factor receptor: Investigation of ligandindependent dimerization in Sf21 microsomal membranes using noncanonical amino acids, Scientific Reports 2016, 6, 34048.

48. Merkel, M.; Arndt, S.; Ploschik, D.; Cserép, G. B.; Wenge, U.; Kele, P.; Wagenknecht H-A., Scope and limitations of typical copper-free bioorthogonal reactions with DNA: Reactive 2’-deoxyuridine triphosphates for postsynthetic labeling, J. Org. Chem. 2016, 81(17), 7527-7538.

47. Söveges, B.; Imre, T.; Szende, T.; Póti, Á. L.; Cserép, G. B.; Hegedűs, T.; Kele, P.; Németh, K., Systematic study of protein labeling by fluorogenic probes using cysteine targeting vinyl sulfone-cyclooctyne tags, Org. Biomol. Chem. 2016, 14, 6071-6078.

46. Kozma, E.; Nikić, I.; Varga, B. R.; Aramburu, I. V.; Kang, J. H.; Fackler, O. T.; Lemke E. A.; Kele, P., Hydrophilic trans-Cyclooctenylated Non-Canonical Amino Acids for Fast Intracellular Protein Labeling, ChemBioChem 2016, 17, 1518-1524.

45. Knorr, G.; Kozma, E.; Herner, A.; Lemke, E. A.; Kele, P., New, red-emitting tetrazine-phenoxazine fluorogenic labels for live-cell intracellular bioorthogonal labeling schemes, Chem. Eur. J. 2016, 22, 8972-8979.

44. Demeter, O.; Fodor, E. A.; Kállay, M.; Mező, G.; Németh, K.; Szabó, P. T.; Kele, P., A Double-Clicking Bis-Azide Fluorogenic Dye for Bioorthogonal Self-Labeling Peptide Tags, Chem. Eur. J. 2016, 22, 6382-6388.

43. Eördögh, Á.; Steinmeyer, J.; Peewasan, K.; Schepers, U.; Wagenknecht, H-A.; Kele, P., Polarity sensitive bioorthogonally applicable far-red emitting labels for postsynthetic nucleic acid labeling by copper-catalyzed and copper-free cycloaddition, Bioconjugate Chem. 2016, 27(2), 457-464.

 

2015

42. Cserép, G. B.; Herner, A.; Kele, P., Bioorthogonal fluorescent labels: a review on combined forces, Methods Appl. Fluoresc. 2015, 3(4), 042001.

41. Domonkos, C.; Zsila, F.; Fitos, I.; Visy, J.; Kassai, R.; Bálint, B.; Kotschy, A., Synthesis and serum protein binding of novel ring-substituted harmine derivatives, RSC Adv. 2015, 5, 53809-53818.

40. Cserép, G. B.; Demeter, O.; Bätzner, E.; Kállay, M.; Wagenknecht, H-A.; Kele, P., Synthesis and Evaluation of Nicotinic Acid Derived Tetrazines for Bioorthogonal Labeling, Synthesis 2015, 47, 2738-2744.

39. Castillo, G.; Pribransky, K.; Mező, G.; Kocsis, L.; Csámpai, A.; Németh, K.; Keresztes, Zs.; Hianik, T., Electrochemical and Photometric Detection of Plasmin by Specific Peptide Substrate, Electroanalysis 2015, 27(3), 789-798.

38. Huber, M. C.; Schreiber, A.; von Olshausen, P.; Varga, B. R.; Kretz, O.; Joch, B.; Barnert, S.; Schubert, R.; Eimer, S.; Kele, P.; Schiller, S. M., Designer amphiphilic proteins as building blocks for the intracellular formation of organelle-like compartments, Nat. Mater. 2015, 14, 125-132.

 

2014

37. Domonkos, C.; Fitos, I.; Visy, J.; Zsila, F., Role of the conformational flexibility of evodiamine in its binding to protein hosts: a comparative spectroscopic and molecular modeling evaluation with rutaecarpine, Phys. Chem. Chem. Phys. 2014, 16(41), 22632-22642.

36. Németh, K.; Domonkos, C.; Sarnyai, V.; Szemán, J.; Jicsinszky, L.; Szente, L.; Visy, J., Cationic permethylated 6-monoamino-6-monodeoxy-β-cyclodextrin as chiral selector of dansylated amino acids in capillary electrophoresis, J. Pharm. Biomed. Anal. 2014, 99, 16-21.

35. Stubinitzky, C.; Cserép, G. B.; Bätzner, E.; Kele, P.; Wagenknecht, H-A., 2’-Deoxyuridine Conjugated with a Reactive Monobenzocyclooctyne as a DNA Building Block for Copper-Free Click-type Postsynthetic Modification of DNA, Chem. Commun. 2014, 50, 11218-11221.

34. Herner, A.; Girona, G. E.; Nikić, I.; Kállay, M.; Lemke, E. A.; Kele, P., New Generation of Bioorthogonally Applicable Fluorogenic Dyes with Visible Excitations and Large Stokes Shifts, Bioconjugate Chem. 2014, 25(7), 1370-1374.

33. Cserép, G. B.; Baranyai, Zs.; Komáromy, D.; Horváti, K.; Bősze, Sz.; Kele, P., Fluorogenic tagging of peptides via Cys residues using thiol-specific vinyl sulfone affinity tags, Tetrahedron 2014, 70, 5961-5965.

32. Bobály, B.; Tóth, E.; Drahos, L.; Zsila, F.; Visy, J.; Fekete, J.; Vékey, K., Influence of acid-induced conformational variability on protein separation in reversed phase high performance liquid chromatography, J. Chromatogr. A 2014, 1325, 155-162.

 

2013

31. Cserép, G. B.; Herner, A.; Wolfbeis, O. S.; Kele, P., Tyrosine specific sequential labeling of proteins, Bioorg. Med. Chem. Lett. 2013, 23, 5776-5778.

30. Herner, A.; Nikić, I.; Kállay, M.; Lemke, E. A.; Kele, P., A new family of bioorthogonally applicable fluorogenic labels, Org. Biomol. Chem. 2013, 11, 3297-3306.

29. Cserép, G. B.; Enyedi, K. N.; Demeter, A.; Mező, G.; Kele, P., NIR Mega-Stokes Fluorophores for Bioorthogonal Labeling and Energy Transfer Systems – An Efficient Quencher for Daunomycin, Chem. Asian J. 2013, 8, 494-502.

28. Kele, P.; Li, X.; Duerkop, A., New luminescent ruthenium probes for detection of diacetyl, Microchem. J. 2013, 108, 156-160.

 

2012

27. Varga, B. R.; Kállay, M.; Hegyi, K.; Béni, Sz.; Kele, P., A non-fluorinated monobenzocyclooctyne for rapid copper-free click reactions, Chem. Eur. J. 2012, 18, 822-828.

 

2011

26. Link, M; Kele, P.; Achatz, D. E.; Wolfbeis, O. S., Brightly fluorescent purple and blue labels for amines and proteins, Bioorg. Med. Chem. Lett. 2011, 21, 5538-5542.

 

2010

25. Mader, H.; Kele, P.; Saleh, S. M.; Wolfbeis, O. S., Upconverting Luminescent Nanoparticles for Use in Bioconjugation and Bioimaging, Curr. Opin. Chem. Biol. 2010, 14, 582–596.

24. Ehrenschwender, T.; Varga, B. R.; Kele, P.; Wagenknecht, H-A., New far-red and near-infrared fluorescent probes with large stokes shifts for dual covalent labeling of DNA, Chem. Asian J. 2010, 8, 1761-1764.

23. Tölgyesi, L.; Kele, P.; Torkos, K., Determination of Propylenethiourea, the Main Metabolite of Propineb, in Tomato by High Performance Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry, Chromatographia 2010, 71 (Suppl.1), 75-80.

22. Nagy, K.; Orbán, E.; Bősze, Sz.; Kele, P., Clickable long-wave "megaStokes" fluorophores for orthogonal chemoselective labeling of cells, Chem. Asian J. 2010, 5, 773-777.

 

2009

21. Lőrincz, K.; Kele, P.; Novák, Z., The sequential Sonogashira-click reaction: A versatile route to 4-aryl-1,2,3-triazoles, Synthesis 2009, 20, 3527-3532.

20. Achatz, D. E.; Mező, G.; Kele, P.; Wolfbeis, O. S., Probing the activity of matrix metalloproteinase II using a sequentially clicked-labeled silica nanoparticle FRET probe, ChemBioChem 2009, 10, 2316-2320.

19. Kele, P.; Li, X.; Link, M.; Nagy, K.; Herner, A.; Lőrincz, K.; Béni, Sz.; Wolfbeis, O. S., Clickable fluorophores for biological labeling – with or without copper, Org. Biomol. Chem. 2009, 7, 3486-3490.

18. Berndl, S.; Herzig, N.; Kele, P.; Lachmann, D.; Li, X.; Wolfbeis, O. S.; Wagenknecht, H-A., Comparison of a nucleosidic vs. non-nucleosidic postsynthetic “Click” modification of DNA with base-labile fluorescent probes, Bioconjugate Chem. 2009, 20(3), 558–564.

17. Kele, P.; Mező, G.; Achatz, D.; Wolfbeis, O. S., Dual labeling of biomolecules by using click chemistry: A sequential approach, Angew. Chem., Int. Ed. 2009, 48(2), 344-347.

 

2008

16. Nagy, K.; Béni, Sz.; Szakács, Z.; Bényei, A.; Noszál, B.; Kele, P.; Kotschy, A., Substituent dependent fluorescence response of diazacrown-based PET sensors, Tetrahedron 2008, 64(27), 6191-6195.

15. Mader, H.; Li, X.; Saleh, S.; Link, M.; Kele, P.; Wolfbeis, O. S., Fluorescent silica nanoparticles, Ann. N. Y. Acad. Sci. 2008, 1130, 218-223.

 

2006

14. Kele, P.; Nagy, K.; Kotschy, A., The development of conformational-dynamics-based sensors, Angew. Chem., Int. Ed. 2006, 45(16), 2565-2567.

13. Kele, P.; Orbulescu, J.; Gawley, R. E.; Leblanc, R. M., Spectroscopic detection of Saxitoxin: an alternative to mouse bioassay, Chem. Commun. 2006, 14, 1494-1496.

 

2005

12. Orbulescu, J.; Kele, P.; Kotschy, A.; Leblanc, R. M., Synthesis and spectroscopy of coumarin derivatives for saxitoxin detection, J. Mater. Chem. 2005, 15(30), 3084-3088.

 

2003

11. Lauer-Fields, J. L.; Kele, P.; Sui, G.; Nagase, H.; Leblanc, R. M.; Fields, G. B., Analysis of matrix metalloproteinase triple-helical peptidase activity with substrates incorporating fluorogenic L- or D-amino acids, Anal. Biochem. 2003, 321(1), 105-115.

 

2002

10. Kele, P.; Orbulescu, J.; Calhoun, T. L.; Gawley, R. E.; Leblanc, R. M., Langmuir Monolayer and Langmuir-Blodgett Film Studies of an Amphiphilic Coumaryl Crown Ether, Langmuir 2002, 18(22), 8523-8526.

9. Kele, P.; Orbulescu, J.; Calhoun, T. L.; Gawley, R. E.; Leblanc, R. M., Coumaryl crown ether based chemosensors: selective detection of saxitoxin in the presence of sodium and potassium ions, Tetrahedron Lett. 2002, 43(25), 4413-4416.

8. Sui, G.; Kele, P.; Orbulescu, J.; Huo, Q.; Leblanc, R. M., Synthesis of a coumarin based fluorescent amino acid, Lett. Pept. Sci. 2002, 8(1), 47-51.

 

2001

7. Huo, Q.; Sui, G.; Zheng, Y.; Kele, P.; Leblanc, R. M.; Hasegawa, T.; Nishijo, J.; Umemura, J., Metal complexation with Langmuir monolayers of histidyl peptide lipids, Chem. Eur. J. 2001, 7(22), 4796-4804.

6. Kele, P.; Orbulescu, J.; Mello, S. V.; Mabrouki, M.; Leblanc, R. M., Langmuir and Langmuir-Blodgett Film Characterization of a New Amphiphilic Coumarin Derivative, Langmuir 2001, 17(23), 7286-7290.

5. Zheng, Y.; Huo, Q.; Kele, P.; Andreopoulos, F. M.; Pham, S. M.; Leblanc, R. M., A New Fluorescent Chemosensor for Copper Ions Based on Tripeptide Glycyl-Histidyl-Lysine (GHK), Org. Lett. 2001, 3(21), 3277-3280.

4. Orbulescu, J.; Mello, S. V.; Huo, Q.; Sui, G.; Kele, P.; Leblanc, R. M., Reexamination of the monolayer properties of a fluorescein amphiphile in Langmuir and Langmuir-Schaefer films, Langmuir 2001, 17(5), 1525-1528.

 

2000

3. Kele, P.; Sui, G.; Huo, Q.; Leblanc, R. M., Highly enantioselective synthesis of a fluorescent amino acid, Tetrahedron: Asymmetry 2000, 11(24), 4959-4963.

2. Huo, Q.; Sui, G.; Kele, P.; Leblanc, R. M., Combinatorial surface chemistry - is it possible?, Angew. Chem., Int. Ed. 2000, 39(10), 1854-1857.

 

1999

1. Kele, P.; Illyés, E.; Mező, G.; Dóda, M.; Mák, M.; Kaposi, A. D.; Sebestyén, F., Fluorescent derivatives of bovine neurotensin 8-13 fragment, Lett. Pept. Sci. 1999, 6(4), 235-238.